Allergic reaction to Omeprazole? There is no good way to know ahead of time if a person is going to have a reaction. We studied 9 patients with adverse reactions to omeprazole. Photosensitivity reaction is found among people who take Omeprazole, especially for people who are female, 60+ old, have been taking the drug for < 1 month. Some people have experienced reactions to omeprazole that closely mimic the symptoms of common allergy attacks such as skin rash, hives, and feelings of tightness in the chest. The presence of cross-reactivity between different members of the group is not clear. The phase IV clinical study is created by eHealthMe based on reports of 289,144 people who have side effects when taking Omeprazole from the FDA, and is updated regularly. Had swelling lips and decided to go to A&E. Pretty stressed about it. I took it for just under 2 weeks and on Friday had a terrible allergic rash with welts and hives everywhere. The experimental skin tests appeared to be helpful in identifying the cause of their allergic reactions, especially when the PPI was the cause.  A number of adverse reactions caused by omeprazole have been reported, including allergic reactions, tachycardia, alimentary tract hemorrhage, liver damage, leucopenia, mental disorders and joint pain (7–18). Clinical symptoms appeared immediately in 8 patients and after … Stomach pain is a possible side effect of omeprazole. Summary: Allergies is reported only by a few people who take Omeprazole. Yes: Theoretically, a person could have an allergic reaction to any medication including omeprazole. Genetic screening revealed that the patient poorly metabolized omeprazole. Omeprazole may cause a serious type of allergic reaction when used in patients with conditions treated with antibiotics. Diagnosed GERD and prescribed the dreaded Omeprazole. This article looks at its uses, dosage, and side effects, as … Omeprazole is a common drug that some people take to treat heartburn, or acid reflux. Call your doctor right away if you or your child has itching, trouble breathing or swallowing, or any swelling of your hands, face, or mouth. Prilosec (omeprazole) is a proton pump inhibitor (PPI) that is used to treat the symptoms of ulcers, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome. IV Prednisone and Piriton. Oral challenges using the culprit PPI resulted in symptoms of an allergic reaction when the skin test was positive, and there was over a 90% correlation between the skin test and the oral challenge. Common side effects of Prilosec include diarrhea, nausea, vomiting, headaches, rash, dizziness, nervousness, abnormal heartbeats, muscle pain, weakness, and infrequently, leg cramps and water retention. The phase IV clinical study is created by eHealthMe based on reports of 289,144 people who have side effects while taking Omeprazole from the FDA, and is updated regularly. I was put on Omeprazole last week (Thursday). Answer Question. However, if a reaction … In general Omeprazole and other ppi drugs are well tolerated. Therefore, severe adverse reactions (allergic shock, rash and diarrhea) experienced by the patient were caused by the accumulation of omeprazole metabolites resulting from its slow metabolism in vivo. Lvl2. By Tuesday my torso was covered in little red spots with some slight itching. Omeprazole works by blocking gastric acid secretion in your stomach which reduces heartburn, ... you should alert your doctor right away as this may indicate an allergic reaction … Is it normal to have a reaction like this with Omeprazole. Though unusual, moderate side effects of omeprazole have been reported by patients as well. 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